Project 1 – Identifying cancer markers better and faster
Exosomes are one of the several types of cell-derived vesicles now recognized as good potential markers of several human diseases, including cancer. However, their use in practical diagnostic tests requires a reliable way to effectively identify their presence, and to do so quickly and at scale.
The funding from the Vissing Foundation to the Clinical Immunological Department at Aalborg University Hospital was for the expansion and further development of the Extracellular Vesicle (EV) Array technology, which has already proven to have considerable diagnostic potential for treating lung cancer.
An EV Array consists of a microchip capable of detecting and identifying extracellular vesicles in biological fluids, and of determining their concentration. The department wants to invest in a specialised micro-array printer that can print these chips in multiples.
This will enable researchers to intensify their efforts with the same resources, and to bring this important diagnostic tool to a level where it can easily be used in ordinary medical contexts and laboratories. The aim is to help identify the presence of cancer cells as early as possible, and thus improve the positive effect of key treatments.